Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits in this search

Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
Purine Nucleoside Phosphorylase (PNP) Homo sapiens (human)	Azetidine based compound, (+/-) 42 (7-{[2-(hydroxymethyl)azetidin-1-yl]methyl}-3H,4H,5...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	1.8000	-49.410	n/a	n/a	n/a	7.7	22
Industrial Research Limited					J Med Chem. 51: 948-56 (2008)
Purine Nucleoside Phosphorylase (PNP) Bos taurus (bovine)	Azetidine based compound, (+/-) 42 (7-{[2-(hydroxymethyl)azetidin-1-yl]methyl}-3H,4H,5...)	B.MOAD GoogleScholar MMDB PDB UniProtKB/SwissProt	PC cid PC sid	PubMed	1.8000	-49.410	n/a	n/a	n/a	7.7	22
Industrial Research Limited					J Med Chem. 51: 948-56 (2008)
Purine Nucleoside Phosphorylase (PNP) Plasmodium falciparum	Azetidine based compound, (+/-) 42 (7-{[2-(hydroxymethyl)azetidin-1-yl]methyl}-3H,4H,5...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/TrEMBL	PC cid PC sid	PubMed	191.00	-37.963	n/a	n/a	n/a	7.7	22
Industrial Research Limited					J Med Chem. 51: 948-56 (2008)