BDBM222051 (3aR,4S,7R,7aS)-2-(4-((E)-3-(4-chlorophenyl)acryloyl)phenyl)-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione (7f)
SMILES Clc1ccc(\C=C\C(=O)c2ccc(cc2)N2C(=O)[C@H]3[C@@H]4C[C@@H](C=C4)[C@H]3C2=O)cc1
InChI Key InChIKey=PJXNRONSFWTMDL-YYBNVSHVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 222051
Affinity DataKi: 0.245nMAssay Description:Binding affinity to human CA2 assessed as inhibition constant using 4-nitrophenylacetate as substrate by spectrophotometrical analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.258nM ΔG°: -13.1kcal/mole IC50: 0.373nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.405nMAssay Description:Binding affinity to human CA1 assessed as inhibition constant using 4-nitrophenylacetate as substrate by spectrophotometrical analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.475nM ΔG°: -12.7kcal/mole IC50: 0.506nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair