BDBM2222 2-Pyridinone derivative 20::3-[2-(4,7-dimethyl-1,3-benzoxazol-2-yl)ethyl]-5-ethyl-6-methyl-1,2-dihydropyridin-2-one::CHEMBL329720::Pyridinone deriv. 15
SMILES CCc1cc(CCc2nc3c(C)ccc(C)c3o2)c(=O)[nH]c1C
InChI Key InChIKey=XKSPCHATHZHOGY-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 2222
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Sharp And Dohme Research Laboratories
Merck Sharp And Dohme Research Laboratories
Affinity DataIC50: 23nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Merck Reserch Laboratories
Curated by ChEMBL
Merck Reserch Laboratories
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Sharp And Dohme Research Laboratories
Merck Sharp And Dohme Research Laboratories
Affinity DataIC50: 28nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair