BDBM22226 3-(5-{5-[3-cyano-4-(propan-2-yloxy)phenyl]-1,2,4-oxadiazol-3-yl}-6-methylpyridin-2-yl)propanoic acid::3-arylpropionic acid derivative, 14

SMILES CC(C)Oc1ccc(cc1C#N)-c1nc(no1)-c1ccc(CCC(O)=O)nc1C

InChI Key InChIKey=BCEWGYMSWUUCKJ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 22226   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM22226(3-(5-{5-[3-cyano-4-(propan-2-yloxy)phenyl]-1,2,4-o...)
Affinity DataEC50:  0.440nMpH: 7.4 T: 2°CAssay Description:EC50s were determined by measuring the binding of [35S]-GTP-gamma-S to S1P receptors expressed in transfected Chinese hamster ovary (CHO) cell membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM22226(3-(5-{5-[3-cyano-4-(propan-2-yloxy)phenyl]-1,2,4-o...)
Affinity DataEC50:  28.6nMpH: 7.4 T: 2°CAssay Description:EC50s were determined by measuring the binding of [35S]-GTP-gamma-S to S1P receptors expressed in transfected Chinese hamster ovary (CHO) cell membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM22226(3-(5-{5-[3-cyano-4-(propan-2-yloxy)phenyl]-1,2,4-o...)
Affinity DataEC50:  2.76E+3nMpH: 7.4 T: 2°CAssay Description:EC50s were determined by measuring the binding of [35S]-GTP-gamma-S to S1P receptors expressed in transfected Chinese hamster ovary (CHO) cell membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed