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BDBM222369 IPR-1176 (22)

SMILES: CCCCCCOc1ccc(cc1)N1C(C(C(=O)c2ccc(Cl)cc2)=C(O)C1=O)c1cccc(F)c1

InChI Key: InChIKey=IYBGOZROZLKFAL-UHFFFAOYSA-N

Data: 1 KI  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222369   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urokinase receptor (uPAR)


(Homo sapiens (Human))
BDBM222369
PNG
(IPR-1176 (22))
Show SMILES CCCCCCOc1ccc(cc1)N1C(C(C(=O)c2ccc(Cl)cc2)=C(O)C1=O)c1cccc(F)c1
Show InChI InChI=1S/C29H27ClFNO4/c1-2-3-4-5-17-36-24-15-13-23(14-16-24)32-26(20-7-6-8-22(31)18-20)25(28(34)29(32)35)27(33)19-9-11-21(30)12-10-19/h6-16,18,26,34H,2-5,17H2,1H3
PDB

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UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
Article
PubMed
1.90E+3n/a 5.38E+4n/an/an/an/an/an/a



Indiana University School of Medicine



Assay Description
Polarized fluorescence intensities were measured using an EnVision Multilabel plate reader (PerkinElmer) with excitation and emission wavelengths of ...


Biochemistry 56: 1768-1784 (2017)


Article DOI: 10.1021/acs.biochem.6b01039
BindingDB Entry DOI: 10.7270/Q2NS0SQC
More data for this
Ligand-Target Pair