BDBM222652 US9315491, MTR-0452::US9801888, Compound MTR-0452

SMILES CCOc1cnc(nc1N1CCOCC1)-c1ccc(NC(=O)Nc2ccc(cc2)S(=O)(=O)N2CCOCC2)cc1

InChI Key InChIKey=IBEWFRNZRQXWPF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222652   

TargetSerine/threonine-protein kinase mTOR(Human)
Development Center For Biotechnology

US Patent
LigandChemical structure of BindingDB Monomer ID 222652BDBM222652(US9315491, MTR-0452 | US9801888, Compound MTR-0452)
Affinity DataIC50: 155nMAssay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Development Center For Biotechnology

US Patent
LigandChemical structure of BindingDB Monomer ID 222652BDBM222652(US9315491, MTR-0452 | US9801888, Compound MTR-0452)
Affinity DataIC50: 155nMpH: 7.5Assay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent