BDBM222659 US9315491, MTR-0462::US9801888, Compound MTR-0462

SMILES CSc1cnc(nc1N1CCOCC1)-c1ccc(NC(=O)Nc2ccncc2)cc1

InChI Key InChIKey=UHLOFOLYVLPASJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222659   

TargetSerine/threonine-protein kinase mTOR(Human)
Development Center For Biotechnology

US Patent
LigandChemical structure of BindingDB Monomer ID 222659BDBM222659(US9315491, MTR-0462 | US9801888, Compound MTR-0462)
Affinity DataIC50: 101nMAssay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Development Center For Biotechnology

US Patent
LigandChemical structure of BindingDB Monomer ID 222659BDBM222659(US9315491, MTR-0462 | US9801888, Compound MTR-0462)
Affinity DataIC50: 101nMpH: 7.5Assay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent