BDBM222972 US9315518, 2-7::US9315518, 5-2

SMILES Cn1c2nc(ccc2n(CC(C)(C)C)c1=O)C1=CC2CCC1CN2C(=O)c1ccon1

InChI Key InChIKey=QMGWNCFCWXUZEI-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 222972   

TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222972(US9315518, 2-7 | US9315518, 5-2)
Affinity DataEC50:  16.0nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222972(US9315518, 2-7 | US9315518, 5-2)
Affinity DataEC50:  9.08nMAssay Description:The stimulation of [35S]-GTPγS binding is a common functional assay to monitor Gαi-coupled receptor in native and recombinant receptor memb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222972(US9315518, 2-7 | US9315518, 5-2)
Affinity DataEC50:  322nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent