BDBM222977 US9315518, 8-38
SMILES Cn1c2nc(ccc2n(CC(C)(C)C)c1=O)C1=CC2CN(CC2C1)C(=O)c1ncco1
InChI Key InChIKey=IOSGOHFTBLNTCF-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 222977
Affinity DataEC50: 54.7nMAssay Description:The stimulation of [35S]-GTPγS binding is a common functional assay to monitor Gαi-coupled receptor in native and recombinant receptor memb...More data for this Ligand-Target Pair
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataEC50: 17.9nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair