BindingDB logo
myBDB logout

BDBM22308 N-{2-[2-(1-benzofuran-2-yl)-1H-indol-3-yl]ethyl}-4-methylbenzene-1-sulfonamide::tryptamine sulfonamide, 40a

SMILES: Cc1ccc(cc1)S(=O)(=O)NCCc1c([nH]c2ccccc12)-c1cc2ccccc2o1

InChI Key: InChIKey=YCHUPXVBZHHWIT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22308   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 15-lipoxygenase


(Oryctolagus cuniculus (rabbit))
BDBM22308
PNG
(N-{2-[2-(1-benzofuran-2-yl)-1H-indol-3-yl]ethyl}-4...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)NCCc1c([nH]c2ccccc12)-c1cc2ccccc2o1
Show InChI InChI=1S/C25H22N2O3S/c1-17-10-12-19(13-11-17)31(28,29)26-15-14-21-20-7-3-4-8-22(20)27-25(21)24-16-18-6-2-5-9-23(18)30-24/h2-13,16,26-27H,14-15H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Bristol-Myers Squibb Co.



Assay Description
The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...


Bioorg Med Chem Lett 15: 1435-40 (2005)


Article DOI: 10.1016/j.bmcl.2004.12.081
BindingDB Entry DOI: 10.7270/Q2T43RD2
More data for this
Ligand-Target Pair