BDBM224056 2-[(6-{[(1r)-1- cyclobutylethyl]amino}- 7-[(trans-4- methylcyclohexyl)meth- yl]-8-[(3r)-3- phenylmorpholin-4-yl]- 7h-purin-2- yl)sulfonyl]ethanol::US9540377, 14.18
SMILES C[C@@H](Nc1nc(nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)S(=O)(=O)CCO)C1CCC1
InChI Key InChIKey=DQMUVIQUQDKGIT-FCBCXNLDSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 224056
Affinity DataIC50: 6.94nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair