BDBM224276 6-(((r)-1-cyclobutylethyl)amino)-7- ((trans-4-ethylcyclohexyl)methyl)-8- (4-isopropylpyridin-2-yl)-7h-purine- 2-carboxylic acid::US9540377, 18.17::US9540377, 18.2
SMILES CC[C@H]1CC[C@H](Cn2c(nc3nc(nc(N[C@H](C)C4CCC4)c23)C(O)=O)-c2cc(ccn2)C(C)C)CC1
InChI Key InChIKey=WLLLONIWVLNEEB-VAMGGRTRSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 224276
Affinity DataIC50: 8.16nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair
Affinity DataIC50: 2.49nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair