BDBM22458 2-(cyclooctylamino)-5-ethyl-5-methyl-4,5-dihydro-1,3-thiazol-4-one::2-Amino-1,3-thiazol-4(5H)-one, 5d

SMILES CCC1(C)SC(NC2CCCCCCC2)=NC1=O

InChI Key InChIKey=YRMKTQIBOUAZCQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22458   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Biovitrum

LigandPNGBDBM22458(2-(cyclooctylamino)-5-ethyl-5-methyl-4,5-dihydro-1...)
Affinity DataKi:  47nM ΔG°:  -9.89kcal/molepH: 7.2 T: 2°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

LigandPNGBDBM22458(2-(cyclooctylamino)-5-ethyl-5-methyl-4,5-dihydro-1...)
Affinity DataIC50: >1.00E+4nMAssay Description:The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed