BDBM224641 US9328111, 14
SMILES O=c1[nH]nc2c3CCNCc3[nH]c3cccc1c23
InChI Key InChIKey=XQOHUNRPGOTXDR-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 224641
Affinity DataIC50: 7.60nMpH: 8.0Assay Description:PARP1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP1 was pre-incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Tankyrase-2 enzymatic assay was conducted using commercial Tankyrase-2 Chemiluminescent Assay Kit (BPS Biosciences) and the protocol with the kit. GS...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:PARP2 and PARP3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with th...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:PARP2 and PARP3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with th...More data for this Ligand-Target Pair