BDBM224985 US9321756, 252

SMILES CC[C@@H]1COCCN1c1nnc(o1)-c1ccc2[nH]cc(-c3cncc(n3)C3CC3)c2c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 224985   

TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM224985(US9321756, 252)
Affinity DataIC50:  29.8nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM224985(US9321756, 252)
Affinity DataIC50:  9.66nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent