BDBM225230 EED226::US11013745, Compound EED226

SMILES: CS(=O)(=O)c1ccc(cc1)-c1cnc(NCc2ccco2)n2cnnc12

InChI Key: InChIKey=DYIRSNMPIZZNBK-UHFFFAOYSA-N

Data: 89 IC50  4 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 93 hits for monomerid = 225230   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent noradrenaline transporter (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A1 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Estrogen receptor (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Estrogen receptor (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Gamma-aminobutyric acid receptor subunit alpha-1 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholine receptor subunit alpha (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 3A (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ZAP-70 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK [2-635] (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Polycomb protein EED (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polycomb protein EED (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polycomb protein EED (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polycomb protein EED (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 4 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polycomb protein EED (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polycomb protein EED (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polycomb protein EED (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polycomb protein EED (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polycomb protein EED (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polycomb protein EED (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polycomb protein EED (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a
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Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
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N-lysine methyltransferase KMT5A (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Histone-arginine methyltransferase CARM1 (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Protein arginine N-methyltransferase 3 [N508S] (Human)	BDBM225230 (EED226 | US11013745, Compound EED226) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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