BDBM22541 Clobenpropit::N''-[(4-chlorophenyl)methyl]{[3-(1H-imidazol-5-yl)propyl]sulfanyl}methanimidamide::VUF 9153::VUF-9153::VUF9153

SMILES: NC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1

InChI Key: InChIKey=UCAIEVHKDLMIFL-UHFFFAOYSA-N

Data: 50 KI  2 IC50  1 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 54 hits for monomerid = 22541   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Mouse)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Mouse)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Guinea pig)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.158	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Histamine receptor H3 (Dog)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hrh3 protein (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hrh3 protein (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Guinea pig)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hrh3 protein (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.339	-12.9	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hrh3 protein (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hrh3 protein (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hrh3 protein (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hrh3 protein (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Mouse)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hrh3 protein (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hrh3 protein (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		2.82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		3.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 3A (Rat)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		7.41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		12.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM22541 (VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		17.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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