BDBM225527 GTC000233A

SMILES: CCN(c1cccc2c1cn[nH]2)c3c(cnc(n3)Nc4ccc5c(c4)S(=O)(=O)NC5)F

InChI Key: InChIKey=LLBDUMUPBVPAMJ-UHFFFAOYSA-N

Data: 90 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 90 hits for monomerid = 225527   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.92	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.69	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.82	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.09	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.51	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.27	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.56	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.38	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.83	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.977	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.02	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.79	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.56	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.48	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.53	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.93	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.91	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.31	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.63	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.66	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.01	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.53	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.59	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.29	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.07	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.96	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.61	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.869	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.87	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.403	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.02	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.61	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.91	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.39	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM225527 (GTC000233A) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.55	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair