BDBM22563 2-arylbenzimidazole derivative, 9::2-{2-chloro-4-[3-(4-methyl-1,4-diazepan-1-yl)propoxy]phenyl}-4,5-dimethyl-1H-1,3-benzodiazole

SMILES CN1CCCN(CCCOc2ccc(-c3nc4ccc(C)c(C)c4[nH]3)c(Cl)c2)CC1

InChI Key InChIKey=RPIXQBZODSVPPC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22563   

TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22563(2-arylbenzimidazole derivative, 9 | 2-{2-chloro-4-...)
Affinity DataKi:  9nM ΔG°:  -11.0kcal/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed