BDBM226171 (6,7-Dimethoxy)-2-((4-(4-chlorophenyl)-5-mercapto-4H-1,2,4-triazol-3-yl)methylthio)-3-(4-methoxyphenyl)quinazolin-4(3H)-one (26)

SMILES COc1ccc(cc1)-n1c(SCc2nnc(S)n2-c2ccc(Cl)cc2)nc2cc(OC)c(OC)cc2c1=O

InChI Key InChIKey=KPCSNNYBAFWVNJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 226171   

TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226171((6,7-Dimethoxy)-2-((4-(4-chlorophenyl)-5-mercapto-...)
Affinity DataIC50:  1.10E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails