BDBM22730 1,2-bis(4-fluorophenyl)ethane-1,2-dione::Benzil-based compound, 8::CHEMBL192410
SMILES Fc1ccc(cc1)C(=O)C(=O)c1ccc(F)cc1
InChI Key InChIKey=BRKULQOUSCHDGS-UHFFFAOYSA-N
Data 10 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 22730
Affinity DataKi: 167nM ΔG°: -9.24kcal/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of human intestinal carboxylesteraseMore data for this Ligand-Target Pair
Affinity DataKi: 229nMAssay Description:Inhibition of human carboxylesterase 1More data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibition of human carboxylesterase 1More data for this Ligand-Target Pair
Affinity DataKi: 231nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 398nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human BChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair