BDBM227644 Histone H4 (1-25)::MSGRGKGGKGLGKGGAKRHRKVLRD

SMILES CSCC[C@H](N)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O

InChI Key

Data  9 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 227644   

TargetBromodomain-containing protein 4 [44-166](Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM227644(Histone H4 (1-25) | MSGRGKGGKGLGKGGAKRHRKVLRD)
Affinity DataKd:  4.80E+3nMpH: 7.5 T: 2°CAssay Description:The experiments were performed in 384-well black small volume microtiter plates(Greiner) in a buffer composed of 50mM Hepes, pH 7.5 (Applichem), 50 m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [44-166,W81A](Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM227644(Histone H4 (1-25) | MSGRGKGGKGLGKGGAKRHRKVLRD)
Affinity DataKd:  5.22E+4nMpH: 7.5 T: 2°CAssay Description:The experiments were performed in 384-well black small volume microtiter plates(Greiner) in a buffer composed of 50mM Hepes, pH 7.5 (Applichem), 50 m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [44-166,P82A](Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM227644(Histone H4 (1-25) | MSGRGKGGKGLGKGGAKRHRKVLRD)
Affinity DataKd:  1.12E+4nMpH: 7.5 T: 2°CAssay Description:The experiments were performed in 384-well black small volume microtiter plates(Greiner) in a buffer composed of 50mM Hepes, pH 7.5 (Applichem), 50 m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [44-166,L94A](Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM227644(Histone H4 (1-25) | MSGRGKGGKGLGKGGAKRHRKVLRD)
Affinity DataKd:  3.98E+4nMpH: 7.5 T: 2°CAssay Description:The experiments were performed in 384-well black small volume microtiter plates(Greiner) in a buffer composed of 50mM Hepes, pH 7.5 (Applichem), 50 m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [44-166,M149A](Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM227644(Histone H4 (1-25) | MSGRGKGGKGLGKGGAKRHRKVLRD)
Affinity DataKd:  7.27E+4nMpH: 7.5 T: 2°CAssay Description:The experiments were performed in 384-well black small volume microtiter plates(Greiner) in a buffer composed of 50mM Hepes, pH 7.5 (Applichem), 50 m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [44-166,D144A](Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM227644(Histone H4 (1-25) | MSGRGKGGKGLGKGGAKRHRKVLRD)
Affinity DataKd:  6.90E+3nMpH: 7.5 T: 2°CAssay Description:The experiments were performed in 384-well black small volume microtiter plates(Greiner) in a buffer composed of 50mM Hepes, pH 7.5 (Applichem), 50 m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [44-166,D145A](Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM227644(Histone H4 (1-25) | MSGRGKGGKGLGKGGAKRHRKVLRD)
Affinity DataKd:  2.38E+4nMpH: 7.5 T: 2°CAssay Description:The experiments were performed in 384-well black small volume microtiter plates(Greiner) in a buffer composed of 50mM Hepes, pH 7.5 (Applichem), 50 m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [44-166,I246A](Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM227644(Histone H4 (1-25) | MSGRGKGGKGLGKGGAKRHRKVLRD)
Affinity DataKd:  1.71E+4nMpH: 7.5 T: 2°CAssay Description:The experiments were performed in 384-well black small volume microtiter plates(Greiner) in a buffer composed of 50mM Hepes, pH 7.5 (Applichem), 50 m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [44-166,Y139F](Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM227644(Histone H4 (1-25) | MSGRGKGGKGLGKGGAKRHRKVLRD)
Affinity DataKd:  8.50E+3nMpH: 7.5 T: 2°CAssay Description:The experiments were performed in 384-well black small volume microtiter plates(Greiner) in a buffer composed of 50mM Hepes, pH 7.5 (Applichem), 50 m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed