BDBM227704 3-{6-(3-chlorophenyl)-7- [(trans-4- methylcyclohexyl)methyl]- 8-[1-(tetrahydro-2h- pyran-4-yl)ethyl]-7h- purin-2-yl}-1,2,4- oxadiazol-5(4h)-one::US9540377, 24.3
SMILES CC(C1CCOCC1)c1nc2nc(nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)-c1noc(=O)[nH]1
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 227704
Affinity DataIC50: 14.2nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair