BDBM22794 1-benzyl-2,3-dihydro-1H-indole-2,3-dione::Isatin-based compound, 14

SMILES: c1ccc(cc1)CN2c3ccccc3C(=O)C2=O

InChI Key: InChIKey=SIISFRLGYDVIRG-UHFFFAOYSA-N

Data: 9 KI  5 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 22794   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldehyde dehydrogenase 1A1 (Human)	BDBM22794 (1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde dehydrogenase 1A1 (Human)	BDBM22794 (1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde dehydrogenase, dimeric NADP-preferring (Human)	BDBM22794 (1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde dehydrogenase, mitochondrial (Human)	BDBM22794 (1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde dehydrogenase 1A1 (Human)	BDBM22794 (1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1 (Human)	BDBM22794 (1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
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Coagulation factor XII (Human)	BDBM22794 (1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...) Show SMILES Show InChI	GoogleScholar	UniChem		870	-8.26	n/a	n/a	n/a	n/a	n/a	7.4	25
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Aldehyde dehydrogenase, dimeric NADP-preferring (Human)	BDBM22794 (1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Liver carboxylesterase 1 (Human)	BDBM22794 (1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldehyde dehydrogenase, dimeric NADP-preferring (Human)	BDBM22794 (1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...) Show SMILES Show InChI	GoogleScholar	UniChem		4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde dehydrogenase, mitochondrial (Human)	BDBM22794 (1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Liver carboxylesterase 1 (Rabbit)	BDBM22794 (1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aldehyde dehydrogenase, mitochondrial (Human)	BDBM22794 (1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM22794 (1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Human)	BDBM22794 (1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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