BDBM22825 7-(trifluoromethyl)-2,3-dihydro-1H-indole-2,3-dione::Isatin-based compound, 45

SMILES: c1cc2c(c(c1)C(F)(F)F)NC(=O)C2=O

InChI Key: InChIKey=MXLDJTXXAYVWDF-UHFFFAOYSA-N

Data: 5 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 22825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Liver carboxylesterase 1 (Rabbit)	BDBM22825 (7-(trifluoromethyl)-2,3-dihydro-1H-indole-2,3-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Liver carboxylesterase 1 (Human)	BDBM22825 (7-(trifluoromethyl)-2,3-dihydro-1H-indole-2,3-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Coagulation factor XII (Human)	BDBM22825 (7-(trifluoromethyl)-2,3-dihydro-1H-indole-2,3-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		3.34E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM22825 (7-(trifluoromethyl)-2,3-dihydro-1H-indole-2,3-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM22825 (7-(trifluoromethyl)-2,3-dihydro-1H-indole-2,3-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair