BDBM22862 2-(2-methyl-1H-imidazol-4-yl)ethan-1-amine::2-Methylhistamine

SMILES Cc1ncc(CCN)[nH]1

InChI Key InChIKey=XDKYTXBAVJELDQ-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22862   

TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit Amsterdam

LigandPNGBDBM22862(2-(2-methyl-1H-imidazol-4-yl)ethan-1-amine | 2-Met...)
Affinity DataKi:  794nM ΔG°:  -8.65kcal/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit Amsterdam

LigandPNGBDBM22862(2-(2-methyl-1H-imidazol-4-yl)ethan-1-amine | 2-Met...)
Affinity DataKi:  794nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM22862(2-(2-methyl-1H-imidazol-4-yl)ethan-1-amine | 2-Met...)
Affinity DataEC50:  794nMAssay Description:Agonist activity at human recombinant histamine H1 receptor expressed in Sf9 cells coexpressing RGS4 by steady-state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit Amsterdam

LigandPNGBDBM22862(2-(2-methyl-1H-imidazol-4-yl)ethan-1-amine | 2-Met...)
Affinity DataEC50:  3.98E+3nMAssay Description:Agonist activity at human recombinant histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2 by steady-state GTPase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed