BDBM22870 13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-piperazin-1-yldibenzo[b,f][1,4]oxazepine::Amoxapine::Asendin::CHEMBL1113::Demolox

SMILES: Clc1ccc2Oc3ccccc3N=C(N3CCNCC3)c2c1

InChI Key: InChIKey=QWGDMFLQWFTERH-UHFFFAOYSA-N

Data: 34 KI  6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 40 hits for monomerid = 22870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent N-type calcium channel subunit alpha-1B (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		1.77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Rat)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		1.99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Rat)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Rat)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Rat)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		6.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent noradrenaline transporter (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Rat)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		30.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Rat)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		30.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Rat)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		39.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Rat)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		40.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(4) dopamine receptor (Rat)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Guinea pig)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		186	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		221	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Rat)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Rat)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Rat)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		409	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Guinea pig)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		4.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H4 receptor (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		5.01E+3	-7.52	n/a	n/a	n/a	n/a	n/a	7.4	37
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Sulfotransferase 1A1 (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		3.50E+4	-5.61	n/a	n/a	n/a	n/a	n/a	7.5	2
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Sulfotransferase 2A1 (Human)	BDBM22870 (CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...) Show SMILES Show InChI	GoogleScholar	UniChem		1.25E+5	-4.91	n/a	n/a	n/a	n/a	n/a	7.5	2
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