BDBM22890 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid::CHEMBL1000::Cetirizine::Levocetirizine

SMILES: OC(=O)COCCN1CCN(CC1)C(c1ccccc1)c1ccc(Cl)cc1

InChI Key: InChIKey=ZKLPARSLTMPFCP-UHFFFAOYSA-N

Data: 9 KI  7 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 22890   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Multidrug and toxin extrusion protein 1 (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.08E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		3.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		5.89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Guinea pig)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		12.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		50.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM22890 (CHEMBL1000 | 2-(2-{4-[(4-chlorophenyl)(phenyl)meth...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	>-7.09	n/a	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair