BDBM229063 US9328099, 21-3

SMILES NC(=O)c1cn(nc1Nc1ccccc1)C1(CC#N)CCN(Cc2cccc(c2)C#N)CC1

InChI Key InChIKey=QRTWEBRTURNQMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 229063   

TargetTyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM229063(US9328099, 21-3)
Affinity DataIC50: 79nMT: 2°CAssay Description:The reactions employed a common peptide substrate, LCB-EQEDEPEGDYFEWLW-NH2 (in-house). The basic assay protocol is as follows: First, 250 nL of dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2017
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM229063(US9328099, 21-3)
Affinity DataIC50: 234nMT: 2°CAssay Description:The reactions employed a common peptide substrate, LCB-EQEDEPEGDYFEWLW-NH2 (in-house). The basic assay protocol is as follows: First, 250 nL of dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2017
Entry Details
US Patent