BDBM22948 1-[(1R,2S)-2-hydroxy-1-(2-naphthalen-1-ylethyl)propyl]-1H-imidazole-4-carboxamide::1-[(3R,4S)-4-hydroxy-1-(naphthalen-1-yl)pentan-3-yl]-1H-imidazole-4-carboxamide::CHEMBL93560::imidazole-4-carboxamide analogue, 5

SMILES C[C@H](O)[C@@H](CCc1cccc2ccccc12)n1cnc(c1)C(N)=O

InChI Key InChIKey=OODDZQQDDOVCFD-SCLBCKFNSA-N

Data  2 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 22948   

TargetAdenosine deaminase(Mus musculus)
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM22948(1-[(1R,2S)-2-hydroxy-1-(2-naphthalen-1-ylethyl)pro...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity to recombinant mouse ADA assessed as inhibition constantMore data for this Ligand-Target Pair
TargetAdenosine deaminase(Homo sapiens (Human))
Fujisawa Pharmaceutical

LigandPNGBDBM22948(1-[(1R,2S)-2-hydroxy-1-(2-naphthalen-1-ylethyl)pro...)
Affinity DataKi:  11nM ΔG°:  -10.7kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
TargetAdenosine deaminase(Homo sapiens (Human))
Fujisawa Pharmaceutical

LigandPNGBDBM22948(1-[(1R,2S)-2-hydroxy-1-(2-naphthalen-1-ylethyl)pro...)
Affinity DataIC50:  16nMAssay Description:Inhibitory concentration against adenosine deaminaseMore data for this Ligand-Target Pair