BDBM229647 BDBM229728::US9334269, K

SMILES CNC(=O)c1cccc(Nc2nccc(n2)N2CC(C2)Oc2ccc(Cl)c(F)c2)c1

InChI Key InChIKey=VXWZOUNYVFDDIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 229647   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM229647(BDBM229728 | US9334269, K)
Affinity DataIC50:  740nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM229647(BDBM229728 | US9334269, K)
Affinity DataIC50:  740nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent