BDBM22984 (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione::Adriamycin::Adriblastina::CHEMBL53463::Doxil::Doxorubicin

SMILES: COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO

InChI Key: InChIKey=AOJJSUZBOXZQNB-UHFFFAOYSA-N

Data: 6 KI  82 IC50  1 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 90 hits for monomerid = 22984   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 1 (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Type II restriction enzyme PstI (Providencia stuartii)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Type II restriction enzyme HindIII (Haemophilus influenzae (strain ATCC 51907 / DSM 11...)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Type II restriction enzyme EcoRI (Escherichia coli)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Type II restriction enzyme BamHI (Bacillus amyloliquefaciens)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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DNA ligase (Enterobacteria phage T4)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Deoxyribonuclease-2-alpha (Pig)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Deoxyribonuclease-1 (Bovine)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Ribonuclease pancreatic (Bovine)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type II restriction enzyme ScaI (Streptomyces caespitosus)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Green monkey)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Mouse)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase (Bovine)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA ligase A (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	8.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Carnitine O-palmitoyltransferase 2, mitochondrial (Rat)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile salt export pump (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+7	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Multidrug resistance-associated protein 1 (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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7-dehydrocholesterol reductase (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, liver isoform (Rat)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Solute carrier organic anion transporter family member 1B1 (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier organic anion transporter family member 1B3 (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Solute carrier organic anion transporter family member 2B1 (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Integrase (Human immunodeficiency virus type 1)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus type 1)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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72 kDa type IV collagenase (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Telomerase reverse transcriptase (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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DNA topoisomerase 2-beta (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate carboxypeptidase 2 (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Human)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Stromelysin-3 (Mouse)	BDBM22984 (Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair