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BDBM23009 3-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-1-[2-(4-phenoxyphenyl)ethyl]urea::N-arachidonoylserotonin urea analogue, 2g

SMILES: Oc1ccc2[nH]cc(CCNC(=O)NCCc3ccc(Oc4ccccc4)cc3)c2c1

InChI Key: InChIKey=DUURBSGUCCFYIB-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23009   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM23009
PNG
(3-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-1-[2-(4-pheno...)
Show SMILES Oc1ccc2[nH]cc(CCNC(=O)NCCc3ccc(Oc4ccccc4)cc3)c2c1
Show InChI InChI=1S/C25H25N3O3/c29-20-8-11-24-23(16-20)19(17-28-24)13-15-27-25(30)26-14-12-18-6-9-22(10-7-18)31-21-4-2-1-3-5-21/h1-11,16-17,28-29H,12-15H2,(H2,26,27,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of Rome La Sapienza



Assay Description
The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...


J Med Chem 50: 6554-69 (2007)


Article DOI: 10.1021/jm070678q
BindingDB Entry DOI: 10.7270/Q2JH3JGS
More data for this
Ligand-Target Pair
Anandamide amidohydrolase


(Rattus norvegicus (rat))
BDBM23009
PNG
(3-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-1-[2-(4-pheno...)
Show SMILES Oc1ccc2[nH]cc(CCNC(=O)NCCc3ccc(Oc4ccccc4)cc3)c2c1
Show InChI InChI=1S/C25H25N3O3/c29-20-8-11-24-23(16-20)19(17-28-24)13-15-27-25(30)26-14-12-18-6-9-22(10-7-18)31-21-4-2-1-3-5-21/h1-11,16-17,28-29H,12-15H2,(H2,26,27,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/a9.037



University of Rome La Sapienza



Assay Description
The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...


J Med Chem 50: 6554-69 (2007)


Article DOI: 10.1021/jm070678q
BindingDB Entry DOI: 10.7270/Q2JH3JGS
More data for this
Ligand-Target Pair