BDBM230657 US9340517, 64
SMILES O=C(NC[C@H]1CCN(CC(c2ccccc2)c2ccccc2)C(=O)[C@@H](CCCN2CCCCC2)N1)c1ccc2ccccc2c1
InChI Key InChIKey=IDXRWSTZYJEJCO-ZEEKBPLESA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 230657
Affinity DataIC50: <100nMpH: 7.4 T: 2°CAssay Description:Assessments of compound binding to human MC5R (hMC5R)) by displacement of an 125I-labeled NDP-MSH receptor ligand peptide were performed essentially ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:Assessments of compound binding to human MC5R (hMC5R)) by displacement of an 125I-labeled NDP-MSH receptor ligand peptide were performed essentially ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.31E+3nMAssay Description:Radioligand binding and cAMP assays were also conducted using membranes and cells expressing MC5R cloned from other species (mouse MC5R membranes wer...More data for this Ligand-Target Pair
Affinity DataIC50: 3.49E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Affinity DataIC50: 9.22E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Affinity DataIC50: 2.24E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMpH: 7.4 T: 2°CAssay Description:Assessments of compound binding to human MC5R (hMC5R)) by displacement of an 125I-labeled NDP-MSH receptor ligand peptide were performed essentially ...More data for this Ligand-Target Pair