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BDBM231620 CG400549::US10071965, Compound CG400549

SMILES: Cc1c(cccc1N)CN2C=CC(=CC2=O)OCCc3cccs3

InChI Key: InChIKey=YCLREGRRHGLOAK-UHFFFAOYSA-N

Data: 6 KI

PDB links: 3 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 231620
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain MRSA252))	BDBM231620 (CG400549 \| US10071965, Compound CG400549) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	-12.1	n/a	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain NCTC 8325 / PS 47))	BDBM231620 (CG400549 \| US10071965, Compound CG400549) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain MRSA252))	BDBM231620 (CG400549 \| US10071965, Compound CG400549) Show SMILES Show InChI	GoogleScholar	UniChem		4.70	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain MRSA252))	BDBM231620 (CG400549 \| US10071965, Compound CG400549) Show SMILES Show InChI	GoogleScholar	UniChem		81.9	-9.66	n/a	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (Escherichia coli (strain K12))	BDBM231620 (CG400549 \| US10071965, Compound CG400549) Show SMILES Show InChI	GoogleScholar	UniChem		81.9	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain MRSA252))	BDBM231620 (CG400549 \| US10071965, Compound CG400549) Show SMILES Show InChI	GoogleScholar	UniChem		99.4	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair