BDBM23165 CHEMBL366208::FTY720-phosphate, (S)-2::[(2S)-2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propoxy]phosphonic acid

SMILES: CCCCCCCCc1ccc(cc1)CC[C@](CO)(COP(=O)(O)O)N

InChI Key: InChIKey=LRFKWQGGENFBFO-UHFFFAOYSA-N

Data: 5 KI  7 IC50  50 EC50

PDB links: 4 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 62 hits for monomerid = 23165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Rat)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.290	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sphingosine 1-phosphate receptor 3 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.01	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	19.9	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	63.1	n/a	n/a	n/a	n/a
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Sphingosine 1-phosphate receptor 4 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 2 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.16E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 2 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 4 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.370	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.30	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Rat)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.290	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.340	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.30	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.370	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.00600	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	94	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.280	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 2 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 4 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.360	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.00800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.00700	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.0700	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.0200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 4 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.670	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.300	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.360	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 4 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	22.2	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	27.8	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sphingosine 1-phosphate receptor 2 (Human)	BDBM23165 (CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
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