BDBM231666 N-(2-(1H-indol-3-yl)ethyl)-3-(3-thiazol-2-ylureido)benzenesulfonamide (1b)

SMILES O=C(Nc1nccs1)Nc1cccc(c1)S(=O)(=O)NCCc1c[nH]c2ccccc12

InChI Key InChIKey=NYYVMDXWTXBRNW-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 231666   

TargetPhenylalanine--tRNA ligase alpha/beta subunit(Pseudomonas aeruginosa)
Astrazeneca R&D Boston

LigandPNGBDBM231666(N-(2-(1H-indol-3-yl)ethyl)-3-(3-thiazol-2-ylureido...)
Affinity DataIC50:  13nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231666(N-(2-(1H-indol-3-yl)ethyl)-3-(3-thiazol-2-ylureido...)
Affinity DataIC50:  2.20nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed