BDBM231676 2-((4-Chlorophenoxy)methyl)-N-(cyanomethyl)thiazole-4-carboxamide (4b)

SMILES Clc1ccc(OCc2nc(cs2)C(=O)NCC#N)cc1

InChI Key InChIKey=DBWAYYAJYBVTAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 231676   

TargetPhenylalanine--tRNA ligase alpha/beta subunit(Pseudomonas aeruginosa)
Astrazeneca R&D Boston

LigandPNGBDBM231676(2-((4-Chlorophenoxy)methyl)-N-(cyanomethyl)thiazol...)
Affinity DataIC50:  1.30E+4nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231676(2-((4-Chlorophenoxy)methyl)-N-(cyanomethyl)thiazol...)
Affinity DataIC50:  100nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed