BDBM23174 6-chloro-1,2-benzoxazol-3-ol::6-chlorobenzo[d]isoxazol-3-ol::CBIO::CHEMBL445990
SMILES Clc1ccc2c(c1)o[nH]c2=O
InChI Key InChIKey=SJAPSPJRTQCDNO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 23174
Affinity DataIC50: 188nMpH: 8.5 T: 2°CAssay Description:D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human DDOMore data for this Ligand-Target Pair
Affinity DataIC50: 507nMAssay Description:Inhibition of human DAOMore data for this Ligand-Target Pair
Affinity DataIC50: 17.2nMAssay Description:Inhibition of human recombinant DAAO expressed in Escherichia coli assessed as H2O2 production from D-serine degradation after 30 mins by fluorescenc...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by whole cell voltage patch clamp techniqueMore data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Binding affinity to human recombinant DAAO by kinetic study scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Binding affinity to human recombinant DAAO by steady state study scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of bovine recombinant DASPO expressed in Escherichia coli preincubated for 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding affinity to human recombinant DAAO by isothermal titration calorimeter analysisMore data for this Ligand-Target Pair