BDBM23223 7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-yl)naphthalen-2-yl]-2,3,8-trihydroxy-6-methyl-4-(propan-2-yl)naphthalene-1-carbaldehyde::CHEMBL51483::Gossypol::Gossypol (C9)::Gossypol, 4::Pogosin::Tash 1::US9115061, Gossypol::cid_3503

SMILES: CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O

InChI Key: InChIKey=QBKSWRVVCFFDOT-UHFFFAOYSA-N

Data: 52 KI  47 IC50  6 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 105 hits for monomerid = 23223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
L-lactate dehydrogenase (Plasmodium falciparum)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.64E+3	n/a	n/a	n/a	n/a	7.0	25
TBA									Citation and Details
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L-lactate dehydrogenase B chain (Bovine)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.54E+3	n/a	n/a	n/a	n/a	7.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
L-lactate dehydrogenase (malaria parasite P. falciparum)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Malate dehydrogenase, mitochondrial (Pig)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Malate dehydrogenase, cytoplasmic (Pig)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Estrogen receptor (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Eukaryotic translation initiation factor 4 gamma 1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
L-lactate dehydrogenase (malaria parasite P. falciparum)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
L-lactate dehydrogenase (Bovine)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
60 kDa heat shock protein, mitochondrial (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Co-chaperonin GroES (Escherichia coli)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Chaperonin GroEL (Escherichia coli)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Co-chaperonin GroES (Escherichia coli)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thiosulfate sulfurtransferase (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aspartyl/asparaginyl beta-hydroxylase (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aspartyl/asparaginyl beta-hydroxylase (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aspartyl/asparaginyl beta-hydroxylase (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aspartyl/asparaginyl beta-hydroxylase (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA repair protein RAD52 homolog (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli (strain K12))	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli (strain K12))	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.71E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.38E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.32E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.65E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.65E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier organic anion transporter family member 1B3 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier organic anion transporter family member 1B1 (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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DNA-3-methyladenine glycosylase (Human)	BDBM23223 (Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair