BDBM23234 1,2,5-oxadiazole, OXD2::4-amino-1,2,5-oxadiazole-3-carboxylic acid

SMILES Nc1nonc1C(O)=O

InChI Key InChIKey=YOXIXLVJYMCCIB-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 23234   

TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM23234(1,2,5-oxadiazole, OXD2 | 4-amino-1,2,5-oxadiazole-...)
Affinity DataKi:  4.20E+5nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University Of Bristol

LigandPNGBDBM23234(1,2,5-oxadiazole, OXD2 | 4-amino-1,2,5-oxadiazole-...)
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
University Of Bristol

LigandPNGBDBM23234(1,2,5-oxadiazole, OXD2 | 4-amino-1,2,5-oxadiazole-...)
Affinity DataIC50: >2.00E+5nMAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed