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BDBM23251 1,2,5-Thiadiazole, TDA1::4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid::LDHA Inhibitor, 1
SMILES: OC(=O)c1ns[nH]c1=O
InChI Key: InChIKey=FVZITYNLUYJDOE-UHFFFAOYSA-N
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| L-lactate dehydrogenase B chain (Human) | BDBM23251![]() (4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid | LD...) | GoogleScholar | UniChem | n/a | n/a | 1.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| L-lactate dehydrogenase A chain (Human) | BDBM23251![]() (4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid | LD...) | GoogleScholar | UniChem | n/a | n/a | 4.50E+5 | n/a | n/a | n/a | n/a | 7.5 | 21 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| L-lactate dehydrogenase B chain (Human) | BDBM23251![]() (4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid | LD...) | GoogleScholar | UniChem | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | 7.5 | 21 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| L-lactate dehydrogenase A chain (Human) | BDBM23251![]() (4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid | LD...) | GoogleScholar | UniChem | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| L-lactate dehydrogenase (Plasmodium falciparum) | BDBM23251![]() (4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid | LD...) | GoogleScholar | UniChem | 290 | -8.91 | 140 | n/a | n/a | n/a | n/a | 7.5 | 25 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||