BindingDB PrimarySearch_ki

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BDBM232517 US9346815, 63::US9604984, Example 63

SMILES: CN(CCC#N)C1CCN(CC1)C(=O)Cn1cc(NC(=O)c2cnn3cccnc23)c(n1)-c1cc(Cl)ccc1OC(F)F

InChI Key: InChIKey=ITNFPSJJBYFVEA-UHFFFAOYSA-N

Data: 4 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 232517
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Human)	BDBM232517 (US9346815, 63 \| US9604984, Example 63) Show SMILES Show InChI	GoogleScholar	UniChem		0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Human)	BDBM232517 (US9346815, 63 \| US9604984, Example 63) Show SMILES Show InChI	GoogleScholar	UniChem		0.340	-12.8	n/a	n/a	n/a	n/a	n/a	7.2	22
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM232517 (US9346815, 63 \| US9604984, Example 63) Show SMILES Show InChI	GoogleScholar	UniChem		0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM232517 (US9346815, 63 \| US9604984, Example 63) Show SMILES Show InChI	GoogleScholar	UniChem		0.700	-12.4	n/a	n/a	n/a	n/a	n/a	7.2	22
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair