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BDBM233075 mtFabH inhibitor, 6

SMILES: CC1=C(O)C(C)(SC1=O)C#CCc1ccc(cc1)[N+]([O-])=O

InChI Key: InChIKey=WVBHFNNUQZZOOH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233075   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
β-Ketoacyl-acyl carrier protein (ACP) synthase III (FabH)


(Mycobacterium tuberculosis)
BDBM233075
PNG
(mtFabH inhibitor, 6)
Show SMILES CC1=C(O)C(C)(SC1=O)C#CCc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C15H13NO4S/c1-10-13(17)15(2,21-14(10)18)9-3-4-11-5-7-12(8-6-11)16(19)20/h5-8,17H,4H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.40E+4n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (...


J Enzyme Inhib Med Chem 25: 240-9 (2010)

More data for this
Ligand-Target Pair