BDBM233101 N-{4-[6-(2-Diethylaminoethoxy)-7-methoxy-quinazolin-4-ylamino]phenyl}-N'-phenylurea hydrochloride (19d)

SMILES CCN(CC)CCOc1cc2c(Nc3ccc(NC(=O)Nc4ccccc4)cc3)ncnc2cc1OC

InChI Key InChIKey=OYEPTZVAPJDGOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 233101   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit?? Lille Nord De France

LigandPNGBDBM233101(N-{4-[6-(2-Diethylaminoethoxy)-7-methoxy-quinazoli...)
Affinity DataIC50:  2.64E+4nMpH: 7.5Assay Description:Kinase assays were performed in 96-well plates (Multiscreen Durapore, Millipore) using [γ-32P]ATP (Amersham Biosciences) and the synthetic polym...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit?? Lille Nord De France

LigandPNGBDBM233101(N-{4-[6-(2-Diethylaminoethoxy)-7-methoxy-quinazoli...)
Affinity DataIC50:  4.30E+3nMpH: 7.5Assay Description:Kinase assays were performed in 96-well plates (Multiscreen Durapore, Millipore) using [γ-32P]ATP (Amersham Biosciences) and the synthetic polym...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed