BDBM233114 N-Cyclohexyl-N'-{4-[6-(2-diethylaminoethoxy)-7-methoxy-quinazolin-4-ylamino]phenyl}urea hydrochloride (19j)

SMILES CCN(CC)CCOc1cc2c(Nc3ccc(NC(=O)NC4CCCCC4)cc3)ncnc2cc1OC

InChI Key InChIKey=LXOCUJRACFRTGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 233114   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit?? Lille Nord De France

LigandPNGBDBM233114(N-Cyclohexyl-N'-{4-[6-(2-diethylaminoethoxy)-7...)
Affinity DataIC50:  8.20E+3nMpH: 7.5Assay Description:Kinase assays were performed in 96-well plates (Multiscreen Durapore, Millipore) using [γ-32P]ATP (Amersham Biosciences) and the synthetic polym...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit?? Lille Nord De France

LigandPNGBDBM233114(N-Cyclohexyl-N'-{4-[6-(2-diethylaminoethoxy)-7...)
Affinity DataIC50:  3.23E+4nMpH: 7.5Assay Description:Kinase assays were performed in 96-well plates (Multiscreen Durapore, Millipore) using [γ-32P]ATP (Amersham Biosciences) and the synthetic polym...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed