BDBM233606 US9353066, 1.59

SMILES FC(F)(F)c1ccnc(Nc2cccc(c2)-c2cccc(Br)c2)n1

InChI Key InChIKey=VWJDDPMVPNXJPW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233606   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM233606(US9353066, 1.59)
Affinity DataIC50: 1.81E+3nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent