BDBM2337 6-benzyl-1-(ethoxymethyl)-5-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione::CHEMBL35033::Coactinon::Emivirine::Emivirine (EMV)::HEPT deriv.::I-EBU::MKC-442

SMILES: CCOCN1C(=C(C(=O)NC1=O)C(C)C)Cc2ccccc2

InChI Key: InChIKey=MLILORUFDVLTSP-UHFFFAOYSA-N

Data: 10 IC50  4 EC50  1 ITC

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 2337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2337 (CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	7.8	37
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Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2337 (CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2337 (CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	7.8	37
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Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM2337 (CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM2337 (CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM2337 (CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM2337 (CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM2337 (CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.20	n/a	n/a	n/a	n/a
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Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM2337 (CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM2337 (CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM2337 (CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM2337 (CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM2337 (CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM2337 (CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TBA									Citation and Details
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