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BDBM233947 US9353090, 75

SMILES: CO[C@@H]1CN(CC[C@@H]1C(O)=O)c1cccc(n1)-c1cc(C)ccc1OCc1ccc2CN(CCc2c1C)C1CCOCC1

InChI Key: InChIKey=ABFBNHKCFMRSHL-KLUITKNGNA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233947   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Soluble Guanylate Cyclases


(Homo sapiens (Human))
BDBM233947
PNG
(US9353090, 75)
Show SMILES CO[C@@H]1CN(CC[C@@H]1C(O)=O)c1cccc(n1)-c1cc(C)ccc1OCc1ccc2CN(CCc2c1C)C1CCOCC1
Show InChI InChI=1/C35H43N3O5/c1-23-7-10-32(30(19-23)31-5-4-6-34(36-31)38-16-12-29(35(39)40)33(21-38)41-3)43-22-26-9-8-25-20-37(15-11-28(25)24(26)2)27-13-17-42-18-14-27/h4-10,19,27,29,33H,11-18,20-22H2,1-3H3,(H,39,40)/t29-,33+/s2
PDB
MMDB

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 15n/an/an/a25



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The sGC cellular activator assay is performed in the presence and absence of 50% human serum (HS) using Chinese hamster ovary cells that have been st...


US Patent US9353090 (2016)


BindingDB Entry DOI: 10.7270/Q2V40T31
More data for this
Ligand-Target Pair