BDBM23475 hydroxamate deriv., 67::methyl (1R,2R)-1-[3-(cyclohexylmethoxy)phenyl]-2-(hydroxycarbamoyl)cyclopropane-1-carboxylate

SMILES COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCC2CCCCC2)c1

InChI Key InChIKey=GZQFXDXWCHYZMR-LPHOPBHVSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23475   

TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM23475(hydroxamate deriv., 67 | methyl (1R,2R)-1-[3-(cycl...)
Affinity DataKi:  900nM ΔG°:  -8.16kcal/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed